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- Currently, no clinical drug-drug interaction studies of remdesivir have been conducted1. However, in vitro, remdesivir is a substrate of CYP2C8, CYP2D6 and PGP, and an inhibitor of CYP3A4, and OATp1B1/B323. Due to antagonism observed in vitro, concomitant use of remdesivir with chloroquine or hydroxychloroquine is not recommended2. There are 376 drugs known to interact with remdesivir, along with 2 disease interactions, and 1 alcohol/food interaction4.Learn more:✕This summary was generated using AI based on multiple online sources. To view the original source information, use the "Learn more" links.Currently, no clinical drug-drug interaction studies of remdesivir have been conducted.www.covid19treatmentguidelines.nih.gov/therapies/…Drug Interactions: Drug-Drug Interactions with remdesivir are not known. Due to antagonism observed in vitro, concomitant use of remdesivir with chloroquine or hydroxychloroquine is not recommended. In vitro, remdesivir is a substrate of CYP2C8, CYP2D6 and PGP. It is an inhibitor of CYP3A4, and OATp1B1/B3.www.health.wa.gov.au/~/media/Corp/Documents/H…No formal drug interaction studies have been conducted involving remdesivir and other medications. In-vitro, remdesivir is a substrate for various drug metabolising enzymes, e.g., CYP2C8, CYP2D6 and CYP3A4, and P- glycoprotein (P-gp) transporters and an inhibitor of various other enzymes, e.g. CYP3A4.www.cec.health.nsw.gov.au/__data/assets/pdf_file/…There are 376 drugs known to interact with remdesivir, along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 2 are major, and 374 are moderate.www.drugs.com/drug-interactions/remdesivir.html
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WEBFeb 29, 2024 · Remdesivir is a nucleotide prodrug that inhibits SARS-CoV-2 replication. It has no clinically significant drug-drug interactions, but may cause gastrointestinal, hepatic, or hypersensitivity reactions.
WEBFeb 28, 2024 · Due to limited clinical experience with remdesivir, randomized clinical trials evaluating data evaluating possible drug-drug …
- Published: 2022/09/08
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